Synthetic Biology Tools for Bioprospecting of Natural Products in Eukaryotes
نویسندگان
چکیده
منابع مشابه
Natural Products and Synthetic Biology
While the phrasing of this tripartite classification was not intended to describe the current state of natural products research, it could have been, as it provides an apt description of the field today. The organic molecules lumped under the term natural products elude an easy definition. They are a structurally diverse collection of molecules produced by organisms in an idiosyncratic fashion,...
متن کاملSynthetic biology of fungal natural products
Synthetic biology is an ever-expanding field in science, also encompassing the research area of fungal natural product (NP) discovery and production. Until now, different aspects of synthetic biology have been covered in fungal NP studies from the manipulation of different regulatory elements and heterologous expression of biosynthetic pathways to the engineering of different multidomain biosyn...
متن کاملIntroduction to the Special Issue “Bioinformatic tools and approaches for Synthetic Biology of natural products”
Microorganisms are the major source for the identification of novel bioactive natural products, which may serve as future lead molecules for drug development to treat infectious and other diseases. However, the research efforts to find suchmolecules have been hampered by high re-discovery rates of known biomolecules and a lack of new innovative screening technologies resulting in reduced screen...
متن کاملBioprospecting for microbial endophytes and their natural products.
Endophytic microorganisms are to be found in virtually every plant on earth. These organisms reside in the living tissues of the host plant and do so in a variety of relationships, ranging from symbiotic to slightly pathogenic. Because of what appears to be their contribution to the host plant, the endophytes may produce a plethora of substances of potential use to modern medicine, agriculture,...
متن کاملBiopiracy of natural products and good bioprospecting practice.
BACKGROUND Biopiracy mainly focuses on the use of biological resources and/or knowledge of indigenous tribes or communities without allowing them to share the revenues generated out of economic exploitation or other non-monetary incentives associated with the resource/knowledge. METHODS Based on collaborations of scientists from five continents, we have created a communication platform to dis...
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ژورنال
عنوان ژورنال: Chemistry & Biology
سال: 2014
ISSN: 1074-5521
DOI: 10.1016/j.chembiol.2014.02.010